Figure 3.

CTR1 status and DNA repair capacity in normal and cancer lung cells. (A,B) Human lung cancer whole-cell lysates analysis of CTR1, XPF and ERCC1 protein levels, respectively, by western blot. Full-lenght membranes are shown on Supplementary Fig. S6. (C,D) HCR assay of lung cancer cell lines transfected with a luciferase plasmid irradiated with 600 J/m² of UVC or treated with 750 nM of cisplatin, respectively. Values are mean ± SEM of three independent experiments (two for the western blot experiments), *P < 0.05, **P < 0.01, ***P < 0.001.