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. 2019 Nov 28;51(11):1–13. doi: 10.1038/s12276-019-0336-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Experimental design. Kidney organoids were differentiated from human iPS cell by an adherent culture differentiation protocol and were purified by microdissection. The microdissected nephron structures were subsequently implanted beneath the kidney capsule of immunodeficient NOD-SCID mice. b Representative images of H&E staining after transplantation. Scale bars, 500 μm. c Representative images of immunohistochemical staining images with HNA after transplantation. Scale bars, 500 μm.