Table 1.
Frequency of manifestations detected by the PDCS compared to the MDS-UPDRS.
| Patients with the symptom/sign | Difference (%) | |||
|---|---|---|---|---|
| PDCS | MDS-UPDRS | |||
| Item | % | Item | % | |
| 1. Bradykinesia | 97.2 | Generated | 99.7 | 2.5 |
| 2. Tremor | 61.8 | Generated | 67.5 | 5.7 |
| 3. Gait | 74.7 | 3.10 | 78.5 | 3.8 |
| 4. Balance | 61.8 | 3.12 | 56.6 | 5.2 |
| 5. Freezing | 34.4 | 3.11 | 33.0 | 1.4 |
| 6. Nocturnal akinesia | 53.2 | 2.9 | 68.8 | 15.6 |
| 7. Fatigue | 81.4 | 1.13 | 76.2 | 5.2 |
| 8. Urinary | 64.1 | 1.10 | 64.6 | 0.5 |
| 9. Cognition | 54.7 | 1.1 | 53.9 | 0.8 |
| 10. Depression/Anxiety | 70.4 | Generated | 78.0 | 7.6 |
| 11. Orth. Hypotension | 36.8 | 1.12 | 49.6 | 12.8 |
| 12. Hallucinations | 23.6 | 1.2 | 20.6 | 3.0 |
| 13. Dyskinesia | 33.0 | Generated | 33.4 | 0.4 |
| 14. Dystonia | 29.1 | 4.6 | 29.5 | 0.4 |
| 15. On/Off | 48.1 | Generated | 60.6 | 12.5 |
| 16. Dopamine Dysreg. Synd. | 11.6 | 1.6 | 10.9 | 0.7 |
| 17. Disability | 83.6 | Part II | 98.3 | 14.7 |
PDCS Parkinson’s Disease Composite Scale, MDS-UPDRS Movement Disorder Society sponsored Unified PD Rating Scale, Orth. Hypotension Orthostatic hypotension, Dopamine Dysreg. Synd. Dopamine dysregulation syndrome, Generated Variable generated in office to be comparable to the corresponding component of the PDCS (see Methods- Data analysis)