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. 2019 Nov 27;9:17653. doi: 10.1038/s41598-019-54099-w

Table 1.

Comparison of the clinicopathological characteristics of the laparoscopic repeat hepatectomy group versus the open repeat hepatectomy group

LRH Open-Re-Hx P
n = 41 n = 96
Age (years)# 65 (25–84) 67 (37–84) 0.851
Gender (male/female) 27/14 66/30 0.842
ASA-PS (3) 4 (9.8) 7 (7.3) 1.000
Tumour type (HCC/metastatic tumour) 19/22 27/69 0.049
Type of approach to the previous hepatectomy (Lap-Hx) 15 (36.6) 4 (4.2) <0.001
Number of the previous hepatectomy (3 or more) 6 (14.6) 31 (32.3) 0.037
Pringle manoeuvre (performed) 17 (41.5) 52 (54.2) 0.195
Time of Pringle manoeuvre (minutes)# 0 (0–133) 16 (0–216) 0.374
Year of surgery (2015–2018) 37 (90.2) 41 (42.7) <0.001
Tumour diameter (mm)# 15.5 (4.0–40) 20.0 (8.0–53) 0.035
Tumour number (multiple) 5 (12.2) 24 (25.0) 0.113
Tumour location (S1, S7 or S8) 13 (31.7) 51 (53.1) 0.025
Tumours located in the ipsilateral of the previous surgical site 19 (46.3) 75 (78.9) 0.001
Tumours located in the adjacent area on the cranial or dorsal side of the previous surgical site 14 (34.1) 47 (49.0) 0.134
Intraoperative blood loss (mL)# 60 (small amount-3,260) 311 (small amount-2,565) <0.001
Operation time (minutes)# 178 (72–368) 203 (64–767) 0.099
Morbidity ≥ Clavien-Dindo grade 3a 1 (2.4) 6 (6.3) 0.674
R0 resection 36 of 39 (92.3) 91 of 93 (97.8) 0.153
Surgical margin (mm)# 4.5 (0–25) 3 (0–30) 0.066
Postoperative hospital stay (days)# 5 (4–41) 9 (4–35) <0.001
Cirrhosis (present) 4 (9.8) 7 (7.3) 0.733

LRH, laparoscopic repeat hepatectomy; Open-Re-Hx, open repeat hepatectomy; ASA-PS, American Society of Anesthesiologists physical status; HCC, hepatocellular carcinoma; Lap-Hx, laparoscopic hepatectomy; S, segment. Values in parentheses are percentages unless indicated otherwise#.value is expressed as the median (range).