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. 2019 Nov 27;9:17653. doi: 10.1038/s41598-019-54099-w

Table 2.

Comparisons of clinical factors of the patients who underwent LRH who were classified as having an intermediate or low risk of massive intraoperative blood loss in accordance with the Iwate difficulty scoring system.

Intermediate (Difficulty index 4 or more) Low (Difficulty index less than 4) P
n = 15 n = 25
Age (years)# 68 (46–84) 65 (25–83) 0.761
Gender (male/female) 11/4 15/10 0.502
ASA-PS (3) 1 (6.7) 3 (12.0) 1.000
Tumour type (HCC/metastatic tumour) 7/8 12/13 1.000
Type of approach to the previous hepatectomy (Lap-Hx) 7 (46.7) 7 (28.0) 0.310
Number of the previous hepatectomy (3 or more) 4 (26.7) 2 (8.0) 0.174
Pringle manoeuvre (performed) 8 (53.3) 9 (36.0) 0.336
Time of Pringle manoeuvre (minutes)# 0 (0–133) 0 (0–108) 0.720
Year of surgery (2015–2018) 14 (93.3) 14 (56.0) 0.015
Tumour diameter (mm) # 20 (7–38) 15 (4–40) 0.041
Tumour number (multiple) 3 (20.0) 2 (8.0) 0.345
Tumour location (S1, S7 or S8) 12 (80.0) 0 <0.001
Tumours located in the ipsilateral of the previous surgical site 12 (80.0) 7 (28.0) 0.003
Tumours located in the adjacent area on the cranial or dorsal side of the previous surgical site 11 (73.3) 3 (12.0) <0.001
Intraoperative blood loss (mL)# 125 (small amount-3,260) 50 (small amount-784) 0.046
Operation time (minutes)# 218 (83–368) 174 (72–355) 0.083
Converted to laparotomy 3 (20.0) 1 (4.0) 0.139
Morbidity ≥ Clavien-Dindo grade 3a 1 (6.7) 0 0.375
Postoperative hospital stay (days) 6 (5–41) 5 (4–17) 0.016

LRH, laparoscopic repeat hepatectomy; ASA-PS, American Society of Anesthesiologists physical status; HCC, hepatocellular carcinoma; Lap-Hx, laparoscopic hepatectomy; S, segment.

Values in parentheses are percentages unless indicated otherwise#.value is expressed as the median (range).