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. 2019 Nov 27;9:17653. doi: 10.1038/s41598-019-54099-w

Table 4.

Comparisons of clinical factors of the patients who underwent LRH with and without tumours located in the adjacent area on the head or dorsal side of the primary site.

Tumours located in the adjacent area on the cranial or dorsal side of the primary site Tumours located in the adjacent area on the caudal or ventral side of the primary site P
n = 14 n = 27
Age (years)# 72 (57–81) 65 (25–84) 0.154
Gender (male/female) 9/5 17/9 1.000
Difficulty index 5 (1–6) 2.5 (1–5) 0.001
ASA-PS (3) 0 4 (14.8) 0.278
Tumour type (HCC/metastatic tumour) 3/11 15/11 0.103
Type of approach to the previous hepatectomy (Lap-Hx) 6 (42.9) 8 (29.6) 0.501
Number of the previous hepatectomy (3 or more) 4 (28.6) 2 (7.4) 0.159
Pringle manoeuvre (performed) 9 (64.3) 8 (29.6) 0.102
Time of Pringle manoeuvre (minutes)# 46 (0–133) 0 (0–128) 0.045
Year of surgery (2015–2018) 14 (100) 14 (51.9) 0.003
Tumour diameter (mm)# 20 (4–40) 15 (6–30) 0.014
Tumour number (multiple) 4 (28.6) 5 (18.5) 0.043
Tumour location (S1, S7 or S8) 9 (64.3) 3 (11.1) 0.001
Tumours located in the ipsilateral of the primary site 13 (92.9) 6 (22.2) <0.001
Intraoperative blood loss (mL) # 284 (small amount-3,260) 50 (small amount-784) 0.009
Operation time (minutes)# 253 (129–368) 170 (72–355) 0.002
Converted to laparotomy 2 (14.3) 2 (7.4) 0.602
Morbidity ≥ Clavien-Dindo grade 3a 1 (7.1) 0 0.350
Postoperative hospital stay (days) 5 (4–41) 5 (4–17) 0.424

LRH, laparoscopic repeat hepatectomy; ASA-PS, The American Society of Anesthesiologists physical status; HCC, hepatocellular carcinoma; Lap-Hx, laparoscopic hepatectomy; S, segment.

Values in parentheses are percentages unless indicated otherwise; #value is expressed as the median (range).