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. 2019 Nov 27;9:17701. doi: 10.1038/s41598-019-54195-x

Table 2.

Pain characterization with the Alberta Breakthrough Pain Assessment.

Question N
Completed by the patients
Q1. Relationship to baseline pain 190
  Brief flare-up of baseline pain 101 (53.2)
  Different from baseline pain 69 (36.3)
  Not sure 20 (10.5)
Q2a. Last time experienced 194
  Today 112 (57.7)
  Yesterday 64 (33.0)
  Before then 18 (9.3)
Q3a. Frequency 182
   Mean (SD) 2.9 (2.1)
Q3b. Frequency 182
  Usual 112 (62.6)
  Better 15 (8.4)
  Worse 52 (29.1)
Q4a. Intensity of pain at peak 195
  Mean (SD) 8.5 (1.5)
Q4b. Intensity of pain at peak 194
  Mild 3 (1.5)
  Moderate 31 (16.0)
  Severe 160 (82.5)
Q5. Location (most frequent - ≥ 5%) 195
  Lumbar 39 (20.0)
  Hips 13 (6.7)
  Abdominal 13 (6.7)
  Back 12 (6.2)
  Thoracolumbar 10 (5.1)
  Thoracic 10 (5.1)
Q6. Quality (Those present in ≥  20%) 195
  Stabbing 113 (57.9)
  Splitting 58 (29.7)
  Sharp 57 (29.2)
  Punishing-Cruel 53 (27.2)
  Heavy 52 (26.7)
  Hot-Burning 50 (25.6)
  Fearful 42 (21.5)
Q7. Time from onset to peak intensity 195
  More than 0 and up to 10 minutes 112 (57.4)
  More than 10 and up to 30 minutes 47 (24.1)
  More than 30 minutes 16 (8,2)
  It is hard to say exactly when it started 20 (10.3)
Q8. Time from onset [take medication] to end of episode 192
  More than 0 and up to 10 minutes 36 (18.8)
  More than 10 and up to 30 minutes 72 (37.5)
  More than 30 minutes 64 (33.3)
  I am not on any breakthrough pain medication 20 (10.4)
Q9. Cause(s) (triggers) (Those present in ≥  20%) 195
  Movement in bed 65 (33.3)
  Walking 62 (31.8)
  Standing 58 (29.7)
  Sitting 38 (19.5)
  Coughing 38 (19.5)
Q10. Predictability 195
  I can never predict when it will occur 38 (19.5)
  I can rarely predict when it will occur 34 (17.4)
  I can sometimes predict when it will occur 40 (20.5)
  I can often predict when it will occur 59 (30.3)
  I can always predict when it will occur 24 (12.3)
Q11. General relief (those present in ≈20% or more patients) 195
  Lying 73 (37.4)
  Use of scheduled pain medication 38 (19.5)
  Unsure 38 (19.5)
Completed by nurses/physicians
Q1. Etiology of breakthrough pain 186
  Pain related to the site of active cancer 145 (78.0)
  Pain related to the whole body or cancer’s systemic effects 11 (5.9)
  Pain related to anticancer treatment 18 (9.7)
  Pain caused by a concurrent disorder 9 (4.8)
  Unknown or uncertain at this time 3 (1.6)
Q2. Inferred pathophysiology of breakthrough pain 186
  Somatic nociceptive 104 (55.9)
  Visceral nociceptive 30 (16.1)
  Neuropathic 37 (19.9)
  Unknown or uncertain at this time 15 (8.1)

All figures are number of patients and percentage except otherwise indicated.

N, number of evaluable patients; SD, standard deviation.