Table 5.

Multivariable linear regression model of QLQ-C30 Global health/QoL at 15 months, adjusted for the significant covariates from each thematic block¹

Independent (at 15 months) variables	Coefficient	(95% CI)
Physical and daily living needs (ref: no need/low level)	0.00
Yes, high level of this domain of needs	− 15.12***	(− 19.45; − 10.79)
Psychological needs (ref: no need/low level)	0.00
Yes, high level of this domain of needs	− 7.33***	(− 11.61; − 3.06)
Health system and information needs (ref: no need/low level)	0.00
Yes, high level of this domain of needs	− 6.25**	(− 10.77; − 1.74)
Domestic status (ref: married/cohabiting)	0.00
Single/never married/divorced/widowed	− 4.31**	(− 7.28; − 1.34)
Comorbidities (ref: none)	0.00
Yes, at least one	− 7.43***	(− 10.56; − 4.30)
Neoadjuvant therapy (ref: none)	0.00
Yes, any (chemotherapy/radiotherapy /both)	− 4.23**	(− 7.68; −0.79)
Had any negative life event in the last 6 months (ref: none)	0.00
Yes, at least one	− 3.97**	(− 6.89; − 1.05)

The model is adjusted for age of respondents; *p < 0.05; **p < 0.01; ***p < 0.001

¹See Supplementary material 4 for the significant covariates from each thematic block