Table 2.
Factors associated with dropout during follow-up, multivariable logistic regression
| Full responders (N = 1246) | Dropoutsa (N = 1204) | Odds of dropout vs. full response | 95% CI | ||
|---|---|---|---|---|---|
| Sex | |||||
| Male | 723 (58%) | 611 (51%) | 1.00 (ref) | ||
| Female | 523 (42%) | 593 (49%) | 1.23* | 1.02–1.47 | |
| Age, M (SD) | 67.90 (9.31) | 70.61 (9.63) | 1.20** | 1.09–1.33 | |
| Partner | |||||
| Yes | 979 (80%) | 863 (73%) | 1.08 | 0.87–1.34 | |
| SES | |||||
| Low | 217 (17%) | 270 (22%) | 0.99 | 0.76–1.23 | |
| Medium | 471 (38%) | 514 (43%) | 1.00 (ref) | ||
| High | 506 (41%) | 381 (32%) | 0.74** | 0.61–0.94 | |
| Unknown/care institution | 52 (4%) | 41 (3%) | 0.74 | 0.46–1.19 | |
| Education | |||||
| Low | 172 (14%) | 304 (25%) | 1.64** | 1.30–2.11 | |
| Medium | 768 (62%) | 692 (57%) | 1.00 (ref) | ||
| High | 298 (24%) | 181 (15%) | 0.87 | 0.69–1.09 | |
| Unknown | 8 (1%) | 27 (2%) | 5.51* | 1.20–25.16 | |
| Stage | |||||
| I | 392 (32%) | 356 (30%) | 0.86 | 0.69–1.07 | |
| II | 432 (36%) | 469 (39%) | 1.00 (ref) | ||
| III | 359 (30%) | 310 (26%) | 0.82 | 0.63–1.06 | |
| IV | 31 (3%) | 40 (3%) | 1.18 | 0.66–2.09 | |
| Unknown | 32 (3%) | 29 (2%) | 0.98 | 0.56–1.70 | |
| Treatment | |||||
| Chemotherapy | 373 (30%) | 333 (28%) | 1.06 | 0.83–1.36 | |
| Radiotherapy | 406 (33%) | 336 (28%) | 0.89 | 0.74–1.08 | |
| Surgery | 1240 (100%) | 1194 (99%) | 0.76 | 0.25–2.32 | |
| Comorbidities | |||||
| 0 | 303 (24%) | 273 (23%) | 1.29 | 0.98–1.67 | |
| 1 | 385 (31%) | 288 (24%) | 0.90 | 0.71–1.16 | |
| 2 | 266 (21%) | 251 (21%) | 1.00 (ref) | ||
| 3 or more | 241 (19%) | 276 (23%) | 0.96 | 0.73–1.25 | |
| Unknown | 51 (4%) | 116 (10%) | 2.21** | 1.42–3.44 | |
| Depressive symptoms | |||||
| Yes | 160 (13%) | 267 (22%) | 1.84** | 1.39–2.44 | |
| Anxiety | |||||
| Yes | 217 (18%) | 255 (21%) | 0.93 | 0.71–1.24 | |
| Physical functioning, M (SD) | 83.7 (18.1) | 77.9 (21.4) | 0.94 | 0.87–1.00 | |
| Role functioning, M (SD) | 83.6 (24.6) | 78.2 (28.1) | 0.96 | 0.92–1.01 | |
| Emotional functioning, M (SD) | 87.5 (17.9) | 84.9 (20.4) | 0.98 | 0.92–1.05 | |
| Social functioning, M (SD) | 87.9 (20.5) | 86.2 (23.1) | 1.05 | 0.99–1.11 | |
| Cognitive functioning, M (SD) | 86.2 (19.8) | 84.1 (20.7) | 1.01 | 0.96–1.07 | |
Note: 285 observations were deleted due to missing values. Odds ratios for age and all EORTC functioning scales are expressed per 10-unit increase. Means (M) with standard deviations (SD) were used to describe normally distributed continuous variables and frequencies with percentages were used to describe categorical variables. Significant odds ratios are in italics
*p < 0.05; **p < 0.01
aDropouts at any wave, excluding participants who dropped out due to death