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. 2019 Nov 27;9:17658. doi: 10.1038/s41598-019-54227-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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eGFR slope (red line) with the light red shaded area representing 95% confidence intervals before and after the AKI_OPT event, modeled using the growth piecewise linear mixed model by incorporating random effects. Blue and orange points represent eGFR measurements before and after enrollment into pre-ESRD program.