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. 2019 Aug 29;9(1):61–78. doi: 10.1016/j.jcmgh.2019.08.008

Figure 5.

Figure 5

Involvement of miR-148a in initiation of chief cell transdifferentiation. (A) Expression of miR-148a in ImChief cells and ImSPEM cells by microRNA assay. Mann-Whitney U test, *P < .05. (B) Expression of miR-148a by microRNA assay in ImChief cells treated with control inhibitor or miR-148a inhibitor. Mann-Whitney U test, *P < .05. (C) Expression of genes related with SPEM cells (He4, Sox9, Cd44v9, and Clu) or chief cells (Pgc and Mist1) in ImChief cells treated with control inhibitor or miR-148a inhibitor by quantitative PCR. Mann-Whitney U test, *P < .05. (D) Expression of miR-148a target genes in ImChief cells treated with control inhibitor or miR-148a inhibitor by quantitative PCR. Mann-Whitney U test, *P < .05.