Figure 5.

Targeting LINC00963 Increases Radiosensitivity of Breast Cancer Cells

(A) Clonogenic survival of MCF-7 and MDA-MB-231 cells transfected with shLINC00963 (shLINC) or shCtrl after exposure to different doses of radiation. *p < 0.05 versus shCtrl-transfected cells. (B) Measurement of ROS levels in transfected cells after 6 Gy radiation. (C) Immunofluorescent staining of γ-H2AX in MCF-7 and MDA-MB-231 cells treated as in (B). The percentage of γ-H2AX-positive cells was quantified. Scale bar, 20 μm. *p < 0.05.