Table 4.
Influence of the aqueous and ethanolic extracts of Dissotis thollonii on haematological in CFA-induced arthritis in rats.
| Treatment | Dose (mg/kg) | Haemoglobin (g/dl) | Hematocrit (%) | Platelet (109/L) | RBC (million/μl) | WBC (109/L) |
|---|---|---|---|---|---|---|
| Healthy control | — | 16.40 ± 0.73 | 38.78 ± 1.03 | 365.25 ± 26.23 | 7.22 ± 0.34 | 7.85 ± 0.44 |
| Arthritic control | — | 9.43 ± 0.20λ | 25.65 ± 1.27λ | 554.75 ± 21.54λ | 3.90 ± 0.37λ | 13.78 ± 0.56λ |
| Diclofenac | 5 | 14.15 ± 0.62b | 33.88 ± 2.59a | 481.75 ± 13.31β | 5.65 ± 0.24a | 10.63 ± 0.64αa |
| Aqueous extract | 250 | 14.28 ± 0.67b | 31.15 ± 1.23α | 478.74 ± 18.71β | 5.74 ± 0.40a | 11.85 ± 0.80λ |
| 500 | 15.55 ± 0.59c | 37.73 ± 1.28c | 383.50 ± 9.75c | 6.93 ± 0.25c | 10.25 ± 0.41b | |
| Ethanolic extract | 250 | 14.33 ± 1.02b | 32.20 ± 1.70 | 426.00 ± 18.11c | 6.31 ± 0.38c | 11.15 ± 0.48β |
| 500 | 16.88 ± 1.32c | 38.38 ± 0.99c | 374.75 ± 8.28c | 7.36 ± 0.29c | 8.28 ± 0.42c |
CFA: complete Freund's adjuvant; RBC: red blood cell; WBC: white blood cell. Each value represents the mean ± ESM of six animals. αp < 0.05; βp < 0.01; λp < 0.001 statistically significant compared with the healthy control. Each value represents the mean ± ESM of 6 animals. ap < 0.05; bp < 0.01; cp < 0.001 statistically significant compared to arthritic control.