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. 2019 Nov 15;10:1380. doi: 10.3389/fphar.2019.01380

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Copyright © 2019 Li, Sun, Zheng, Zong, Li, Meng, Li, Liu, Wang and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of the oxytocin receptor (OTR) antagonist or vasopressin-1a receptor (V1AR) antagonist on OT-induced enhancement. In the presence of conivaptan (1 µg/site, n = 5), a selective V1AR antagonist, markedly blocked OT-induced augment of scratching behavior induced by CQ (A). However, pretreatment with the OTR antagonist L-368,899 (1 µg/site, n = 4) did not show any suppression effect (B). Vehicle, 0.1% dimethyl sulfoxide. n.s., no significance, *: p < 0.05.