Fig. 2.

Fibrosis of cardiac muscles. a Sirius red staining shows more severe fibrosis in the liraglutide groups among all groups (scale bar: 500 µm). Representative images of anterior wall in short axis of the heart are shown. b The rates of fibrosis area/whole area were calculated using the Image J software. Fibrosis was exacerbated by liraglutide administration in a dose-dependent manner. *p < 0.005 (n = 4 in each group) vs. HF group