Fig. 4.

Visualization and alignment of repeat and spacer content for each detected CRISPR locus. Each diamond represents a CRISPR repeat, while each colored square represents a CRISPR spacer. Unique color combinations indicate distinct nucleotide compositions. Missing spacers are indicated by a gray “x” box. a Repeats are highly conserved across all isolates within CRISPR-Cas types II-A and I-E. b Some degree of shared evolutionary history is represented by the conservation of at least the first two ancestral spacers (on the right) in the type II-A spacer alignment