Table 2.
Parameters of the model
| Parameter | Description | Value | Unit | Additional information |
|---|---|---|---|---|
| T | Travel time using the fastest route on a road network | min | Calculated with network analysis | |
| VOT | The value of time based on the average hourly income of a zip code area | EUR | Average hourly gross wage converted from the monthly gross wage in 2017 | |
| P | Patient’s productivity coefficient | 1.00 or 0.35 | Used as weight | Depicts patient’s lost contribution to the society. Working time is valued as 100% and leisure time as 35% of the hourly wage |
| Tp | Private car parking time | 5 | min | Added to the total journey time |
| D | Travel distance calculated from the fastest route on a road network | km | Calculated with network analysis | |
| VOC | Vehicle operating cost | |||
| Private car | 0.45 | EUR/km | Includes fuel cost and vehicle maintenance and depreciation costs | |
| Taxi | 1.60 | EUR/km | Most common fare per km | |
| Ta | Network access time | |||
| Taxi service time | 5 | min | Added to the total journey time | |
| Waiting time in a bus stop | 7 | min | Added to the total journey time | |
| Walking time to a bus stop | 5 | min | Added to the total journey time | |
| Walking time from a bus stop to home or clinic | 5 | min | Added to the total journey time | |
| F | Fare paid for the journey | |||
| One-way bus fare | 2.00, 3.80 or 5.00 | EUR | Fare depends on the fare zone | |
| Taxi initial fixed charge | 5.90 | EUR | Most common fee in the study area | |
| Tinr | Patient time loss associated with INR monitoring | 40 | min | Blood test and the adjustment of warfarin dosage |
| Cinr | Cost of the INR monitoring visit | 25.00 | EUR | Includes healthcare personnel costs (result examination, warfarin dosage counseling via SMS or phone call and making the next appointment) based on the service provider prices for nurse/doctor phone consultation |
| Ct | Cost of the INR blood test | 10.50 | EUR | Sampling 7.50 € + test 3.00 € |
| Cm | Cost of the medication | |||
| Warfarin | 3.90/2.20 | EUR/mo. | Retail price (excl. VAT)/distributor’s price. Calculated with the average consumption of 5 mg/day | |
| Apixaban | 82.40/59.50 | EUR/mo. | Retail price (excl. VAT)/distributor’s price | |
| Dabigatran | 82.40/59.50 | EUR/mo. | Retail price (excl. VAT)/distributor’s price | |
| Rivaroxaban | 74.00/59.40 | EUR/mo. | Retail price (excl. VAT)/distributor’s price | |
| Edoxaban | 73.80/59.40 | EUR/mo. | Retail price (excl. VAT)/distributor’s price |
All monetary values, except the value of time, are based on the prices (EUR) on October 1, 2018