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. 2019 Nov 27;16:238. doi: 10.1186/s12974-019-1630-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — PGRN deficiency promoted neuroinflammation by ex vivo ELISA test. Supernatants of ex vivo tissue cultures were measured by ELISA for TNFα (a), IL-1β (b), IL-6 (c), and IL-10 (d). n = 5 per group. One-way ANOVA and Turkey’s post hoc test were used. *p < 0.05 WT-SCI vs Grn^−∕−-SCI groups. ns, not significant