Table 1.
Description of scoring summary used for the histology evaluation of bladder from mice
| Score/Type | Description | |
|---|---|---|
| Inflammation | 0 | no presence of inflammatory cells |
| 1 | low presence of inflammatory cells | |
| 2 | moderate presence of inflammatory cells | |
| 3 | high presence of inflammatory cells | |
| N, L, P, M | Type of inflammatory cells - Neutrophils, Lymphocytes, Plasma cells, Macrophages | |
| Hyperplasia | 0 | no hyperplasia (less than 2 cells in urothelial layer) present |
| 1 | low hyperplasia (between 3 and 5 cells in urothelial layer) present | |
| 2 | severe hyperplasia (more than 5 cells in urothelial layer) present | |
| D, F, M | Diffuse, Focal, Multi-focal hyperplasia | |
| Carcinoma in situ (CIS) | 0 | no CIS present |
| Yes | CIS present | |
| Carcinomaa | 0 | no carcinoma present |
| Yes | carcinoma present |
Notes: aIncluding adenocarcinoma, squamous cell carcinoma and transitional cell carcinoma