Table 3.
Patient and tumour characteristics by Consensus Molecular Subtype
CMS1 (n = 60) | CMS2 (n = 145) | CMS3 (n = 38) | CMS4 (n = 17) | P-value* | ||
---|---|---|---|---|---|---|
(n) | % | % | % | % | ||
Age | ||||||
< 60y | 48 | 3.3 | 18.6 | 15.8 | 11.8 | 0.0188 |
61-80y | 170 | 48.3 | 53.8 | 60.5 | 52.9 | |
> 80y | 90 | 48.3 | 27.6 | 23.7 | 35.3 | |
Gender | ||||||
F | 163 | 73.8 | 42.8 | 63.2 | 52.9 | 0.0009 |
M | 145 | 26.2 | 57.2 | 36.8 | 47.1 | |
Site | ||||||
Colon | 253 | 98.3 | 75.9 | 84.2 | 64.7 | < 0.0001 |
Rectum | 55 | 1.7 | 24.1 | 15.8 | 35.3 | |
Side | ||||||
Left | 172 | 20 | 71 | 50 | 76.5 | < 0.0001 |
Right | 136 | 80 | 29 | 50 | 23.5 | |
Stagea | ||||||
1 | 53 | 16.7 | 17.2 | 28.9 | 11.8 | 0.01449 |
2 | 128 | 55 | 44.8 | 26.3 | 23.5 | |
3 | 105 | 26.7 | 29.7 | 42.1 | 47.1 | |
4 | 22 | 1.7 | 8.3 | 2.6 | 17.6 |
Patient and tumour characteristics by Consensus Molecular Subtype (CMS) given as percentages. N, total number of patients per group; P-value* is derived from analysis of classified tumours only and a P-value of < 0.05 is considered significant; y years, F Female, M Male; a Post-operative Tumour-Node-Metastasis staging