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. 2019 Nov 19;9:1176. doi: 10.3389/fonc.2019.01176

Table 1.

Clinical features and relative expression of miR-9 in glioblastoma (110 cases).

Clinical variables Num miR-9 relative expression X2/H P value
High expression Low expression
Total 110 55 55
Gender
   Male 51 27 (49.1) 24 (43.6) 0.329 0.566
   Female 59 28 (50.9) 31 (56.9)
Age (y)
    <50 48 22 (40.0) 26 (47.3) 0.591 0.442
   >50 61 33 (60.0) 29 (52.7)
Recurrences
   Yes 44 16 (29.1) 28 (50.9) 5.455 0.020
   No 66 39 (70.9) 27 (49.1)
Onset time (m)
    ≤ 12 43 18 (32.7) 25 (45.5) 1.871 0.171
   >12 67 37 (67.3) 30 (54.5)
Num of lobes involved
   Single 64 40 (72.7) 24 (43.6) 9.565 0.002
   Multiple 46 15 (27.3) 31 (56.4)
Pre-op KPS score
   ≥80 59 33 (60.0) 26 (47.3) 1.791 0.181
    <80 51 22 (40.0) 29 (52.7)
Post-op KPS score
   ≥80 658 431 (53.4) 27 (46.6) 10.584 0.445
    <80 452 124 (46.2) 328 (53.8)
Tumor size
    <3 cm 35 17 (30.9) 18 (32.7) 3.251 0.197
   3–5 cm 45 19 (34.5) 26 (47.3)
   >5 cm 30 19 (34.5) 11 (20.0)
Adjuvant therapy
   Yes 52 23 (41.8) 29 (52.7) 1.313 0.252
   No 58 32 (58.2) 26 (47.3)
Degree of tumor resection
   Totally 30 12 (21.8) 18 (32.7) 0.157 0.692a
   Most partially/partially 54 33 (60.0) 21 (38.1)
   Biopsy 26 10 (18.2) 16 (29.1)
Survivals
    <6 m 37 10 (18.2) 27 (49.1) 15.209 <0.001
   6–12 m 29 14 (25.5) 15 (27.3)
   >12 m 44 31 (56.4) 13 (23.6)

Pre-op, pre-operative; Post-op, post-operative; Num, number.

a

Degree of tumor resection is a hierarchical variable was used by the Kruskal Wallis H-test of non-parametric test.