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. 2019 Nov 27;19:337. doi: 10.1186/s12906-019-2749-4

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — TXYF protects epithelial permeability in the colon of IBS-D rats. a ELISAs showed that the OCLN and ZO1 contents were significantly decreased in the model, rifaximin and TXYF groups before treatment but increased in the rifaximin and TXYF groups after treatment. b Western blot analysis for OCLN and ZO1 in colonic tissue samples. c qRT-PCR for OCLN and ZO1 in colonic tissue samples. ^aP < 0.05 vs the blank group. ^bP < 0.05 vs before treatment. ^cP < 0.05 vs the model group