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. 2019 Nov 27;19:242. doi: 10.1186/s12911-019-0973-y

Table 1.

Summary of clinical trial termination rates within levels of each structured variable

Characteristic Level total_n Completed Terminated
Primary Purpose Missing 29484 0.94 0.06
Primary Purpose Basic Science 4915 0.94 0.06
Primary Purpose Device Feasibility 52 0.83 0.17
Primary Purpose Diagnostic 3858 0.87 0.13
Primary Purpose Educational/Counseling/Training 118 0.89 0.11
Primary Purpose Health Services Research 1971 0.96 0.04
Primary Purpose Other 795 0.91 0.09
Primary Purpose Prevention 11939 0.93 0.07
Primary Purpose Screening 723 0.93 0.07
Primary Purpose Supportive Care 3491 0.91 0.09
Primary Purpose Treatment 76625 0.88 0.12
Intervention Type Behavioral 10147 0.97 0.03
Intervention Type Biological 7770 0.90 0.10
Intervention Type Combination Product 8 1.00 0.00
Intervention Type Device 10957 0.88 0.12
Intervention Type Diagnostic Test 73 0.96 0.04
Intervention Type Dietary Supplement 3811 0.95 0.05
Intervention Type Drug 65364 0.88 0.12
Intervention Type Genetic 500 0.90 0.10
Intervention Type Other1 11302 0.93 0.07
Intervention Type Procedure 8908 0.89 0.11
Intervention Type Radiation 751 0.78 0.22
Study Phase Early Phase 1 915 0.88 0.12
Study Phase Missing1 54082 0.93 0.07
Study Phase Phase 1 17396 0.91 0.09
Study Phase Phase 1/Phase 2 4432 0.84 0.16
Study Phase Phase 2 22544 0.85 0.15
Study Phase Phase 2/Phase 3 2423 0.87 0.13
Study Phase Phase 3 17992 0.89 0.11
Study Phase Phase 4 14187 0.90 0.10
Intervention Model Missing2 27542 0.93 0.07
Intervention Model Crossover Assignment 11597 0.95 0.05
Intervention Model Factorial Assignment 1836 0.94 0.06
Intervention Model Parallel Assignment 61036 0.90 0.10
Intervention Model Sequential Assignment 49 0.90 0.10
Intervention Model Single Group Assignment 31911 0.86 0.14
Allocation Missing3 45626 0.90 0.10
Allocation Non-Randomized 14325 0.88 0.12
Allocation Random Sample 40 0.93 0.07
Allocation Randomized 73980 0.91 0.09
Enrollment Group > 1000 7151 0.96 0.04
Enrollment Group 0-100 80755 0.87 0.13
Enrollment Group 101-1000 42683 0.94 0.06
Enrollment Group Missing4 3382 0.95 0.05