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. 2019 Nov 27;14:214. doi: 10.1186/s13014-019-1418-6

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — DNA damage signalling and repair gene expression in irradiated isogenic FaDu, FaDu-RR, and 2A3 cells. a Gene expression in 5 Gy-irradiated FaDu-RR cells relative to 5 Gy-irradiated FaDu cells. b Gene expression in 5 Gy-irradiated 2A3 cells relative to 5 Gy-irradiated FaDu cells. Volcano plots show the fold change in gene expression and statistical significance (p-value). The horizontal line shows the statistical significance threshold (p-value < 0.05). Two vertical dashed lines show the threshold of over-expressed (right) and under-expressed genes (left). The solid vertical line shows no change in gene expression. Symbols represent the mean gene expression of each tested gene in 5 Gy-irradiated radioresistant FaDu-RR and radiosensitive 2A3 cells relative to 5 Gy-irradiated parental FaDu cells from three independent experiments