Table 1.
Half-maximal inhibitory concentration (IC50) values of isogenic cells to chemotherapeutics
| Cytotoxic drug (μg/mL) | FaDu | FaDu-RR | Fold-potentiationa | 2A3 | Fold-potentiationa |
|---|---|---|---|---|---|
| Cisplatin | 0.16 ± 0.007 | 0.284 ± 0.02b | 1.8 | 0.1 ± 0.03 | 0.7 |
| Oxaliplatin | 0.75 ± 0.15 | 1.12 ± 0.15c | 1.5 | 0.41 ± 0.13 | 0.5 |
| Bleomycin | 551 ± 132 | 521 ± 18 | 0.9 | 249 ± 63 | 0.5 |
aFold-potentiation compared to parental FaDu cell line. b significant difference compared to FaDu and 2A3 cells. c significant difference compared to 2A3. Values are AM ± SEM