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. 2019 Nov 26;9(1):1696517. doi: 10.1080/20013078.2019.1696517

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Comparison of methods to isolate sEVs from mouse plasma. (a) Scheme for sEV isolation from mouse plasma through SEC, UC, and PEG-based isolation. (b) Protein profiles were examined by SDS-PAGE (0.1 µg protein/lane). (c) Morphology was examined by TEM. TEM images in low (left) and high (right) magnification are shown. Representative TEM images were analysed by Image J software to measure the size histogram.