Table 1.
Studies reporting herpes simplex virus type 1 and 2 seroprevalence among different populations in Nigeria.
| Authors (Year) | Year (s) of Data Collection | Geopolitical Zone | Study Site | Study Design | Sampling Method | Population | Serological Assay | Sample Size, No. | HSV Seroprevalence, No. (%) |
|---|---|---|---|---|---|---|---|---|---|
| Herpes Simplex Virus Type 1 | |||||||||
| Healthy Children Populations (n = 2) | |||||||||
| Shiabu et al. [16] | 2011 | North-West | Hospital | CS | Conv. | 0-5-y-old male children | ELISA | 198 | 108 (54.5) |
| Shiabu et al. [16] | 2011 | North-West | Hospital | CS | Conv. | 0-5-y-old female children | ELISA | 179 | 110 (61.5) |
| Healthy Adult Populations (n = 1) | |||||||||
| Drisu et al. [24] | N/A | North-Central | Community | CS | Conv. | 15-49-y-old women | ELISA | 330 | 318 (96.4) |
| Herpes Simplex Virus Type 2 | |||||||||
| Healthy Adult Populations (n = 8) | |||||||||
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 16-20-y-old pregnant women | ELISA | 7 | 2 (28.6) |
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 21-25-y-old pregnant women | ELISA | 98 | 38 (38.8) |
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 26-30-y-old pregnant women | ELISA | 242 | 96 (39.7) |
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 31-35-y-old pregnant women | ELISA | 225 | 109 (48.4) |
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 36-40-y-old pregnant women | ELISA | 86 | 59 (68.6) |
| Kalu [13] | 2011–2012 | South-South | Hospital | Cohort | Conv. | 41-45-y-old pregnant women | ELISA | 16 | 8 (50.0) |
| Drisu et al. [24] | N/A | North-Central | Community | CS | Conv. | 15-49-y-old women | ELISA | 330 | 254 (77.0) |
| Kalu [14] | 2011–2012 | South-South | Hospital | CS | Conv. | 15-45-y-old pregnant women | ELISA | 410 | 194 (47.3) |
| Clinical Adult Population (n = 7) | |||||||||
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 21-30-y-old male patients attending an STI clinic | EIA | 3 | 2 (66.6) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 21-30-y-old female patients attending an STI clinic | EIA | 78 | 65 (83.3) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 31-40-y-old male patients attending an STI clinic | EIA | 10 | 10 (100.0) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 31-40-y-old female patients attending an STI clinic | EIA | 42 | 38 (90.4) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 41-50-y-old male patients attending an STI clinic | EIA | 1 | 1 (100.0) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 41-50-y-old female patients attending an STI clinic | EIA | 11 | 10 (90.9) |
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 51-60-y-old female patients attending an STI clinic | EIA | 3 | 3 (100.0) |
| Clinical Mixed Age Population | |||||||||
| Agabi et al. [25] | N/A | North-Central | Hospital | CS | Conv. | 11-20-y-old female patients attending an STI clinic | EIA | 14 | 12(85.7) |
| Other Populations (n = 7) | |||||||||
| Dada et al. [12] | 1990–1991 | South-West | Community | CS | Conv. | >20-y-old female sex workers | ELISA | 796 | 470(59.0) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 11-20-y-old HIV patients | ELISA | 12 | 3(25.0) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 21-30-y-old HIV patients | ELISA | 27 | 22(81.5) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 31-40-y-old HIV patients | ELISA | 98 | 46(46.9) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 41-50-y-old HIV patients | ELISA | 65 | 39(60.0) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 51-60-y-old HIV patients | ELISA | 43 | 26 (60.5) |
| Odebisi-Omokanye et al. [17] | N/A | North-Central | Hospital | CS | Conv. | 61-70-y-old HIV patients | ELISA | 31 | 19 (61.3) |
Abbreviations: N/A, Not Available; CS, Cross-Sectional; Conv, Convenience; ELISA, Enzyme-Linked Immunosorbent Assay; HSV-1, Herpes Simplex Virus Type 1; HSV-2, Herpes Simplex Virus Type 2; EIA, Enzyme Immunoassay; HIV, Human Immunodeficiency Virus; STI, Sexually Transmitted Infection.