Figure 3.

(A) OCT examination showed marked differences of the retinal thickness among the four animal groups. The retinal thickness in MNU group was not significant different from that in the MNU + lutein group. The retinal thickness in AST-treated mice was significantly larger compared with the MNU + lutein group. (B) The retina structure of the normal control group was highly organized, whereas the retinal structure of MNU group was severely destroyed. The ONL in the AST-treated mice was efficiently preserved. The average ONL thickness in MNU + AST group mice was significantly greater compared to MNU + lutein group. (C) Numerous TUNEL-labeled cells located in the ONL of the MNU group. The TUNEL-labeled cells in the MNU + AST group were prominently less compared with the MNU group. The AI of the MNU + AST group was significantly smaller compared with MNU group (ANOVA analysis followed by Bonferroni’s post hoc analysis was performed, ^#p < .01, for differences between groups; n = 10).