Figure 4.

(A) Representative LFPs waveforms of each animal group. (B) Electrodes of MEA were classified into three categories: the central, the mid-peripheral, and the peripheral channels. The LFPs waveforms of the MNU group were undetectable. Conversely, the LFPs waveforms of the MNU + AST group were effectively preserved. (C) The mean amplitude of LFPs in the MNU group was significantly smaller compared with normal controls. The mean amplitude of LFPs in the MNU + AST group was significantly larger compared with the MNU group. In the MNU + AST group, the LFPs in peripheral region had larger amplitudes than those in the mid-peripheral and central regions (ANOVA analysis followed by Bonferroni’s post hoc analysis was performed, ^#p < .01, for differences between groups; n = 10).