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. 2019 Nov 26;8(1):1711–1720. doi: 10.1080/22221751.2019.1694395

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Antigen variants detected in B. pertussis circulating in the metropolitan area of Barcelona from 1986 to 2015. (A) Pertussis toxin. (B) Pertussis toxin promoter type. (C) Pertactin. (D) Type 3 fimbriae. P1: exclusive use of whole cell vaccine; P2: transition from whole cell vaccine to acellular vaccine; P3: exclusive use of acellular vaccine.