Table 3.
Effects of C. verum on mean distribution of fibroblasts, fibrocytes per one mm2 of the wound tissue and epithelium thickness (µm) and oedema in different groups on different days.
Groups | Oedema | Immune cell | Vessels | Fibroblast | Collagen | Epithelium |
---|---|---|---|---|---|---|
Day 3 | ||||||
Control | ++++ | 105 ± 5.98a | 0.22 ± 0.21a | 0.5 ± 0.29a | – | – |
5% C. verum-treated | +++ | 82.8 ± 4.99b | 6.5 ± 1.29b | 4.50 ± 1.29b | + | 15.25 ± 4.11a |
10% C. verum-treated | +++ | 78.25 ± 5.91b | 7.75 ± 0.96b | 6.50 ± 1.29b | + | 24.95 ± 9.71b |
Day 7 | ||||||
Control | +++ | 84.1 ± 6.47a | 1.8 ± 0.85a | 6.10 ± 1.84a | + | 11.95 ± 1.17a |
5% C. verum-treated | ++ | 60.2 ± 3.86b | 14 ± 2.71b | 18.25 ± 2.50b | ++ | 69.25 ± 4.57b |
10% C. verum-treated | + | 45.9 ± 3.42c | 20.25 ± 2.63c | 23.75 ± 2.63b | +++ | 95.50 ± 3.10c |
Day 14 | ||||||
Control | ++ | 67.2 ± 3.12a | 4.5 ± 1.11a | 5.00 ± 0.80a | +++ | 78.50 ± 4.35a |
5% C. verum-treated | + | 40.75 ± 3.6b | 8±−.82b | 12.75 ± 2.21b | ++++ | 162.75 ± 34.13b |
10% C. verum-treated | – | 27.5 ± 2.22c | 8.25 ± 1.26b | 14.75 ± 3.40b | ++++ | 208.50 ± 36.68b |
Note: Data are presented as the mean ± S.D. There are significant differences between groups with different superscripts (a,b,cp < 0.05 versus controls).