Figure 2.

Effects of ICD and ACD in eliciting spontaneous scratching and wiping behaviors in male mice. Mean bouts of spontaneous scratching (A) and mean number of wipes (B) were obtained before and 24 hours after the first, second, and third challenge with SADBE in mice that were previously sensitized to the chemical (ACD) or previously exposed only to the acetone vehicle (ICD). Control mice received only the acetone before and during challenge. *P < 0.05, **P < 0.01, error bars: SEM. n = 12 mice/group. ACD, allergic contact dermatitis; ICD, irritant contact dermatitis.