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. 2019 Nov 22;10:1392. doi: 10.3389/fphys.2019.01392

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Copyright © 2019 Widing, Pellegrini, Larsson and Perchiazzi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maximal transpulmonary pressure (P_TP,_MAX) in relation to positive end-expiratory pressure (PEEP) level. The graph shows the P_TP,_MAX and standard error observed during peak flow conditions. The P_TP increases with increasing PEEP level. The changes are statistically significant as shown by regression analysis. When correcting for multivariable comparison, according to Pearson’s correlation, the changes still show significance (p < 0.01).