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. 2019 Nov 29;4:51. doi: 10.1038/s41392-019-0086-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — HOXB13 is downregulated and associated with survival in RCC. a The intersections of DEGs identified from five datasets (GSE20916, GSE37892, GSE39582, GSE14333 and GSE39084) showed three common differentially expressed genes (DEGs). b The numbers of upregulated and downregulated genes among differentially expressed genes in RCC compared to LCC identified from each of the five datasets are shown. Overall survival analyses with data from c LCC patients, d RCC patients and e all CRC patients according to the expression level of HOXB13 were conducted. The expression levels of HOXB13 were compared between left-sided and right-sided CRC patient data in the f GSE14333, g GSE20916, h GSE37892, i GSE39084 and j GSE39582 datasets. ***P < 0.001, ****P < 0.0001