Table 1.
Stroma-corrected ZEB1 expression is inversely associated with immune cell infiltration and activity in breast tumors.
| Step of immune response | Description | Partial corr. | p.value |
|---|---|---|---|
| Step 1 | Cancer Cell Ag Release | −0.1373 | 5.26E-06 |
| Step 2 | Cancer Ag Presentation | 0.1469 | 1.08E-06 |
| Step 3 | Priming and Activation | −0.2222 | 1.10E-13 |
| Step 4: Recruitment | T cell.recruiting | −0.3592 | 1.36E-34 |
| CD4 T cell.recruiting | −0.2060 | 6.22E-12 | |
| CD8 T cell.recruiting | −0.3026 | 1.45E-24 | |
| Th1 cell.recruiting | −0.2746 | 2.40E-20 | |
| Dendritic cell.recruiting | −0.2695 | 1.27E-19 | |
| Th22 cell.recruiting | −0.2518 | 2.95E-17 | |
| Macrophage.recruiting | −0.4693 | 6.69E-61 | |
| Monocyte.recruiting | −0.1986 | 3.57E-11 | |
| Neutrophil.recruiting | −0.2568 | 6.67E-18 | |
| NK cell.recruiting | −0.3840 | 1.11E-39 | |
| Eosinophil.recruiting | −0.4318 | 8.16E-51 | |
| Basophil.recruiting | −0.3382 | 1.26E-30 | |
| Th17 cell.recruiting | −0.1572 | 1.78E-07 | |
| B cell.recruiting | −0.1088 | 0.000317 | |
| Th2 cell.recruiting | −0.3104 | 8.07E-26 | |
| Treg cell.recruiting | −0.1810 | 1.71E-09 | |
| MDSC.recruiting | −0.2294 | 1.67E-14 | |
| Step 5 | Tumor infiltration | −0.1302 | 1.59E-05 |
| Step 6 | Recognition | −0.0379 | 0.210775 |
| Step 7 | Cell killing | −0.1947 | 8.56E-11 |