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. 2019 Nov 28;9:17792. doi: 10.1038/s41598-019-54513-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Estimated survival among NSCLC patients, SEER-Medicare dataset 2010–2012; For all NSCLC patients, the top panel in this figure shows a Kaplan-Meier estimate of survival for each group of patients treated with and without bevacizumab, and the middle panel shows a conditional survival curve in which each observation is weighted with respect to odds of bevacizumab treatment. At the bottom, a table of the Kaplan-Meier estimated proportion of patients at risk is provided. Due to non-proportional hazards, weighted estimation of hazard ratios was performed to yield an average hazard ratio of mortality associated with the use of bevacizumab.