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. 2019 Nov 28;9:17843. doi: 10.1038/s41598-019-54434-1

Figure 2.

Figure 2

Example of ROI correction using semiautomatic segmentation by the first version of the CAD software (sCAD). (a) Image of a 51-year-old female patient with a 4.6-cm FNA-proven benign mass at the right thyroid. (b) When the user selected two points indicating the top-left and bottom-right points of a ROI box enclosing the thyroid nodule of interest, the initial semiautomatic segmentation results calculated by the CAD software included the adjacent normal thyroid tissue and trachea. (c) The user then manually selected a point at the correct nodule margin where the contour was miscalculated, and the CAD software correctly recalculated the contour of the nodule. The segmentation results shown in (c) were used for analysis. The nodule was assessed as possibly benign by both dCAD and sCAD.