Table 2.
Overall diagnostic performance of CAD systems and radiologists for diagnosing thyroid malignancy in the validation data set (n = 286).
| Performance measures | Radiologists | dCAD | sCAD | p-Value | p-Value | ||
|---|---|---|---|---|---|---|---|
| Radiologists vs. dCAD | Radiologists vs. sCAD | dCAD vs. sCAD | |||||
| Sensitivity |
94.2% (89.3, 97.0) |
91.0% (85.5, 94.6) |
90.4% (84.7, 94.1) |
0.137 | |||
| Specificity |
76.9% (68.6, 83.6) |
80.0% (72.4, 85.9) |
58.5% (49.9, 66.6) |
<0.001 | 0.431 | 0.001 | <0.001 |
| PPV |
83.1% (76.5, 88.0) |
84.5% (78.3, 89.2) |
72.3% (65.6, 78.2) |
<0.001 | 0.552 | 0.001 | <0.001 |
| NPV |
91.7% (84.9, 95.7) |
88.1% (81.0, 92.9) |
83.5% (74.4, 89.8) |
0.084 | |||
| Accuracy |
86.4% (81.7, 90.0) |
86.0% (81.6, 89.5) |
75.9 (70.6, 80.5) |
<0.001 | 0.862 | <0.001 | <0.001 |
Note – 95% confidence intervals are shown in parentheses.