Table 3.
Diagnostic performance according to the experience level of the radiologists.
| Performance measures | Radiologists | dCAD | sCAD | p-Value | p-Value | ||
|---|---|---|---|---|---|---|---|
| Radiologists vs. dCAD | Radiologists vs. sCAD | dCAD vs. sCAD |
|||||
| Nodules Assessed by Experienced Radiologists (n = 184) | |||||||
| Sensitivity |
92.9% (85.8, 96.6) |
90.8% (83.3, 95.2) |
90.8% (83.3, 95.2) |
0.599 | |||
| Specificity |
87.2% (78.3, 92.8) |
84.9% (75.9, 90.9) |
58.1% (47.7, 67.9) |
<0.001 | 0.527 | <0.001 | <0.001 |
| PPV |
89.2% (81.5, 93.9) |
87.3% (79.4, 92.4) |
71.2% (62.7, 78.4) |
<0.001 | 0.476 | <0.001 | <0.001 |
| NPV |
91.5% (83.1, 95.9) |
89.0% (80.2, 94.2) |
84.8% (73.2, 91.9) |
0.318 | |||
| Accuracy |
90.8% (83.3, 95.2) |
88.0% (82.6, 92.0) |
75.5% (68.8, 81.2) |
<0.001 | 0.284 | <0.001 | <0.001 |
| Nodules Assessed by Inexperienced Radiologists (n = 102) | |||||||
| Sensitivity |
96.6% (87.5, 99.1) |
91.4% (81.3, 96.3) |
89.7% (78.9, 95.3) |
0.145 | |||
| Specificity |
56.8% (41.6, 70.9) |
70.5% (55.9, 81.8) |
59.1% (44.0, 72.7) |
0.221 | |||
| PPV |
74.7% (62.9, 83.7) |
80.3% (68.8, 88.3) |
74.3% (62.5, 83.3) |
0.270 | |||
| NPV |
92.6% (74.8, 98.1) |
86.1% (70.7, 94.1) |
81.3% (63.9, 91.4) |
0.241 | |||
| Accuracy |
79.4% (70.1, 86.4) |
82.4% (73.9, 88.5) |
76.5% (67.2, 83.8) |
0.409 | |||
Note – 95% confidence intervals are shown in parentheses.