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. 2019 Nov 28;9:17776. doi: 10.1038/s41598-019-54347-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The circle plot compares pathogenic CNVs found in: (first, the outhermost double track) our study of a cohort of 420 individuals with neurodevelopmental disorders (ND), derived from a complex population in the south of Brazil, mostly composed by the Portuguese conquerors, German and Italian immigrants, besides descendants of slaves and of Amerindians; (second double track from the border) studies of 1.245 individuals from five affected European cohorts; (third double track) studies of 15.901 individuals from two affected North American cohorts; (fourth, innermost double track) the pathogenic CNVs detected exclusively in our study, when compared to the other studies in the plot.