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. 2019 Nov 28;9:17858. doi: 10.1038/s41598-019-54491-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Box plots of Dice similarity coefficient (DSC) for method in comparison to the reference standard for the Radboudumc test dataset. Corresponding data are listed in Table 3. The central lines show the median values, the box edges depict the 25th and 75th percentiles and the whiskers indicate the extremes at 1.5 interquartile range excluding the two outliers, depicted as +.