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. 2019 Nov 28;10:5419. doi: 10.1038/s41467-019-13457-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Fully automatic sequence design of ten diverse scaffolded DNA origami objects with 6HB edges. a Representative (middle) AFM and (bottom) TEM images for a star lattice and curved beam lattice are shown. Target 2D wireframe objects (with green lines) and DNA-based atomic models with b triangular and c quadrilateral meshes, d without internal mesh, and e with irregular meshes. The top zoomed-in image on each panel is the representative object that is the most deformed and the image below represents the object that is the least deformed in shape. Scale bars in zoomed-in and zoomed-out AFM and TEM images are 50 and 200 nm, respectively.