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. 2019 Nov 28;7(22):e14286. doi: 10.14814/phy2.14286

Figure 5.

Figure 5

Effects of single or combined treatment with ipragliflozin and pioglitazone on liver histopathological scores for (a) microvesicular steatosis, (b) hepatocellular hypertrophy, (c) inflammation, and (d) fibrosis in type 2 diabetic mice with NASH. Ipragliflozin and/or pioglitazone was orally administered to diabetic mice with NASH for 4 weeks. Values indicate individual data and median for six animals per group. *p < .05 versus normal group, # p < .05 versus vehicle group, $ p < .05 versus pioglitazone (10 mg/kg) group