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Effects of single or combined treatment with ipragliflozin and pioglitazone on oxidative stress parameters, plasma (left) and hepatic (right) levels of (a) TBARS and (b) protein carbonyl, in type 2 diabetic mice with NASH. Ipragliflozin and/or pioglitazone was orally administered to diabetic mice with NASH for 4 weeks. Values indicate mean ± SEM for six animals per group. *p < .05 versus normal group, # p < .05 versus vehicle group, $ p < .05 versus pioglitazone (10 mg/kg) group
