Table 1A.
Demographics and clinical data of Brazilian patients grouped by histological phenotypes.
| AR n=26 |
CR n=27 |
GN n=14 |
TX n=17 |
p | |
|---|---|---|---|---|---|
| Recipient age (years) | 42 ± 3 | 40 ± 2 | 47 ± 3 | 48 ± 3 | NS |
| Female recipients (%) | 11 (48%) | 13 (48%) | 6 (43%) | 8 (47%) | NS |
| Recipient race (W/NW) | 6/20 | 10/17 | 11/3 | 10/7 | 0.05 |
| Deceased donor (%) | 13 (50%) | 14 (52%) | 6 (43%) | 4 (24%) | NS |
| HLA mismatch | 3.2 ± 0.3 | 2.3 ± 0.3 | 2.6 ± 0.4 | 2.8 ± 0.4 | NS |
| PRA ≥ 20 (%) | 6 (27%) | 6 (%) | 5 (36%) | 4 (23.5%) | NS |
| Induction therapy‡ (%) | 26 (100%) | 26 (96%) | 13 (93%) | 15 (88%) | NS |
| C4d positive | 3 (11%) | 4 (15%) | 0 | 0 | NS |
| Time to biopsy (median months; IQR) | 13 (6 – 30) | 48 (24 – 90) | 50 (27 −140) | 36 (27–65) | 0.001 |
| eGFR (mL/min/1.73m2) (median ; IQR) | 28.4 (17.5 – 41.8) | 28.9 (26.0 – 38.3) | 24.2 (18.2 – 39.5) | 72.8 (58.2 – 83.8) | 0.001 |
| IS at biopsy TAC/EC-MPS/Pred (%) | 20 | 18 | 8 | 11 | NS |
| CSA/EC-MPS/Pred (%) | 1 | 1 | 2 | 0 | NS |
| mTORi/TAC/Pred (%) | 3 | 3 | 0 | 2 | NS |
| mTORi/EC-MPS/Pred (%) | 2 | 3 | 1 | 3 | NS |
| Others | 0 | 2 | 3 | 1 | NS |
| Death-censored graft loss | 8 (35%) | 10 (37%) | 9 (64%) | 0 | NS |
| Patient death (%) | 1 (3.8%) | 2 (7%) | 1 (7%) | 0 | NS |
| Donor age (years) | 43 ± 10 | 47 ± 12 | 48 ± 13 | 39 ± 9 | NS |
| Female donor (%) | 20 (77%) | 11 (41%) | 7 (50%) | 11 (65%) | 0.03 |
Values are expressed as mean ± standard deviation unless otherwise indicated. interquartile range (IQR); NS, not significant; AR, Acute Rejection; CR (IFTA/Chronic rejection); GN, glomerular disease recurrence; TX, excellent functioning kidney; HLA, Human Leukocyte Antigen; PRA, Panel Reactive Antibody; W; white; NW (black, brown and mulatto).