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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Lancet Psychiatry. 2019 Oct 17;6(12):1054–1067. doi: 10.1016/S2215-0366(19)30213-5

Table 3.

Health outcomes associated with drinking reductions as defined by the WHO drinking risk levels (drinks per day) and change in WHO risk level between Wave 1 (2001-2002) and Wave 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)10,210-212

Wave 1 WHO risk level
and change by Wave 2
Alcohol
dependence
SF-12 impaired mental
health functioning
Liver disease Depression and/or
anxiety disorder
Drug use disorder
Very high risk
 No change R R R R R
 Decreased by 1 level
 Decreased by 2 levels
 Decreased by 3 levels
 Became abstainer --- ---
High risk
 Increased
 No change R R R R R
 Decreased by 1 level
 Decreased by 2 levels
 Became abstainer --- ---
Moderate risk
 Increased
 No change R R R R R
 Decreased by 1 level
 Became abstainer --- ---
Low risk
 Increased
 No change R R R R R
 Became abstainer ---

▼= decreased risk; ▲ = increased risk; ▼/▲= p≤0·05; /= p>0·05; R = reference group; --- = contrast could not be computed because the prevalence of condition at Wave 2 was 0·0%

Note: AUDIT-C results are not included because there were very high proportions of participants at the WHO very-high-risk and high-risk drinking levels with Wave 1 positive AUDIT-C scores; therefore, adjusted odds of positive Wave 2 AUDIT-C scores by change in WHO drinking risk level could not be produced because the regression models used to produce them did not converge.