Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Toxicity profile during treatment
| Adverse event n, (%) | Capecitabine (n = 41) | S-1 (n = 40) | |||
| Any grade | Grade ≥ 3 | Any grade | Grade ≥ 3 | P value1 | |
| Nausea | 11 (26.8) | 1 (2.4) | 13 (32.5) | 1 (2.5) | 1.000 |
| Vomiting | 4 (9.8) | 1 (2.4) | 5 (12.5) | 0 | 1.000 |
| Diarrhea | 4 (9.8) | 0 | 3 (7.5) | 0 | |
| Stomatitis | 7 (17.1) | 0 | 6 (15.0) | 1 (2.5) | 0.494 |
| Hand-foot syndrome | 13 (31.7) | 6 (14.6) | 2 (5.0) | 0 | 0.026 |
| Anemia | 12 (29.3) | 0 | 9 (22.5) | 0 | |
| Neutropenia | 7 (17.1) | 0 | 3 (7.5) | 0 | |
P value for grade ≥ 3 adverse events.
