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. 2019 Nov 15;11(11):1011–1020. doi: 10.4251/wjgo.v11.i11.1011

Table 3.

Effect level comparison for early-onset colorectal cancer

Later-onset CRC
Control
Cohen’s d Effect level Cohen’s d Effect level
Gender (%)
Male -0.02 - 0.07 +
Female 0.02 + -0.07 -
Ethnicity (%)
Caucasian -0.20 - 0.09 +
African-American 0.04 + 0.05 +
Asian -0.03 - -0.03 -
Symptoms (%)
Abdominal pain 0.14 + 0.37 + +
Rectal pain 0.10 + 0.48 + +
Altered bowel function 0.03 + 0.41 + +
Rectal bleeding 0.02 + 0.55 + + +
Weight loss -0.10 - 0.48 + +
Family History (%)
Of cancer 0.14 + 0.59 + + +
Of GI malignancy 0.21 + + 0.80 + + + +
Of polyps 0.08 + 0.50 + + +
Social History (%)
Tobacco use -0.04 - 0.22 + +
Alcohol use -0.04 - 0.13 +
Comorbidities (%)
Colitis 0.02 + 0.34 + +
BMI ≥ 30 0.03 + 0.25 + +
Hypertension -0.36 - 0.25 + +
Hyperlipidemia -0.39 - 0.21 + +
Polyp history (%) -0.07 - 0.53 + + +

CRC: Colorectal cancer; GI: Gastrointestinal; BMI: Body mass index.