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. 2019 Nov 22;13:1239. doi: 10.3389/fnins.2019.01239

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Copyright © 2019 Deng, Mu, Miao, Liu, Zhou, Huang, Zhang, Wang, Yang, Qian, Wang, Guo, Zhang, Liao, Wan, Lu and Zou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of gastrodin on DM-induced pathological changes in the cerebellar cortex. H&E staining (A–C) and Nissl staining (D–F) of the cerebellar cortex in NC9W, DM9W + S, and DM9W + G groups. Black arrow indicates Purkinje cells. Note the drastic reduction of Purkinje neurons in the DM9W + S group. Note also the wide interstitial spaces around the Purkinje cells in the same group. In DM9W + G, the incidence of Purkinje cells is increased; moreover, the neuropil is now more compact. Magnification: ×400. Bar = 50 μm.