GC-depleted fungal proteomes are enriched in lysine, isoleucine and asparagine. Average predicted amino acid abundance per clade, ordered in decreasing GC content, is shown across the fungal kingdom. GC-rich fungal phyla are enriched in alanine, glycine, arginine, proline and valine. Asparagine is particularly enriched in Neocallimastigomycota, similar to P. falciparum, another extremely GC depleted organism.